tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate, (3R)-3-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine - Names and Identifiers
tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate, (3R)-3-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine - Physico-chemical Properties
Molecular Formula | C10H20N2O2
|
Molar Mass | 200.28 |
Density | 1.044±0.06 g/cm3(Predicted) |
Boling Point | 280.3±13.0 °C(Predicted) |
Flash Point | 144.5°C |
Vapor Presure | 0.000323mmHg at 25°C |
Appearance | Liquid |
Color | Colorless to yellow |
BRN | 10537871 |
pKa | 10.12±0.29(Predicted) |
Storage Condition | 2-8°C |
Sensitive | Air Sensitive |
Refractive Index | 1.4780 |
tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate, (3R)-3-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36 - Irritating to the eyes
R22 - Harmful if swallowed
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
WGK Germany | 3 |
TSCA | No |
tert-Butyl (3R)-3-(aminomethyl)pyrrolidine-1-carboxylate, (3R)-3-(Aminomethyl)-1-(tert-butoxycarbonyl)pyrrolidine - Introduction
(R)-N-Boc-3-(aminomethyl)pyrrolidine is an organic compound with the following properties:
1. Appearance: (R)-N-Boc-3-(aminomethyl)pyrrolidine is a white solid.
2. Solubility: (R)-N-Boc-3-(aminomethyl)pyrrolidine has good solubility in common organic solvents.
3. Stability: (R)-N-Boc-3-(aminomethyl)pyrrolidine is relatively stable under regular experimental conditions, but it may decompose under high temperature, oxidant or strong acid conditions.
4. Use: (R)-N-Boc-3-(aminomethyl)pyrrolidine is an important organic synthesis intermediates, commonly used in the synthesis of drugs, pesticides and other organic compounds. It can be used as a chiral reagent for the preparation of chiral target compounds.
5. Preparation method: (R)-N-Boc-3-(aminomethyl)pyrrolidine preparation method is more complex, the common method is the nucleophilic substitution reaction of pyrrolidine and ethyl carbamate with 1-butoxycarbonylcyclobutane.
6. Safety Information: (R)-N-Boc-3-(aminomethyl)pyrrolidine is generally less toxic under proper use and storage conditions. However, appropriate safety measures should still be taken, such as wearing protective gloves and glasses to avoid inhalation or contact with skin. When handling and disposing, follow local regulations.
Last Update:2024-04-09 20:45:29